Tilly Corteen-Coleman, 16, took the wickets of Lauren Winfield-Hill and Paige Scholfield from successive balls, but Marizanne Kapp (26*) anchored the remainder of her side’s innings as they closed on 79-4.
Brave’s Smriti Mandhana was run out for just two early in the reply, but Wyatt was dropped twice in her innings, by Mady Villiers when on five and by Capsey, having made 14.
Maia Bouchier (16) and Freya Kemp (3) fell cheaply, but Wyatt dominated the strike to lead the defending champions towards their target and then smashed Sophia Smale for six over square leg to seal Brave’s first success in six matches.